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Recombinant Human Galectin-1 (LGALS1) Protein


Species Reactivity

Human

Source

Prokaryotic expression

Host

E. coli

Synonyms

Gal-1; LGALS1 ; HLBP14; HBL; HPL; Galaptin

Concentration

1 mg/mL

Form

Lyophilized or Liquid

Purity

> 95% as determined by SDS-PAGE

Residues

P09382

Tag

N-terminal His-tag

Purification

Affinity purification

Molecular Weight(MW)

16 kDa

Applications

Western blotting,ELISA;SDS-PAGE;Antigen;

Cat

AP50086HU

Size

100μg 500μg

Price

Inquire

Availability

3-5 working days

Manual

Inquire
Product Overview:
LGALS1 contains four exons. The galectin-1 protein is 135 amino acids in length and highly conserved across species. It can be found in the nucleus, the cytoplasm, the cell surface and in the extracellular space. Galectins in general lack a traditional signal sequence, but are still secreted across the plasma membrane. This non-traditional secretion requires a functional glycan binding site. Galectin 1 contains a single carbohydrate recognition domain through which it can bind glycans both as a monomer and as a homodimer. Dimers are non-covenantly bound and will spontaneously disassociate in low concentration.[3] Galectin 1 does not bind glycans when oxidized.[4] Having 6 cysteine residues, the oxidation state has a significant effect on the protein structure. The oxidized form is reported to have alternative functions not involving carbohydrate binding.
Usage:
Reconstitute in PBS or others.
Stability:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage:
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
Stroage Buffer:
Lyophilized from 20mM PB, 300mMNaCl,pH7.7
Precautions:
This product is for research use only, not for diagnostic or therapeutic use.