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Recombinant Human Major Histocompatibility Complex Class I Related Gene Protein (MR1) Protein


Species Reactivity

Human

Source

Prokaryotic expression

Host

E. coli

Synonyms

MR1; HLALS; MR-1

Concentration

1 mg/mL

Form

Lyophilized or Liquid

Purity

> 90% as determined by SDS-PAGE

Residues

Q95460

Tag

N-terminal His-tag

Purification

Affinity purification

Molecular Weight(MW)

12 kDa

Applications

Western blotting,ELISA;SDS-PAGE;Antigen;

Cat

AP50148HU

Size

100μg 500μg 1mg

Price

Inquire

Availability

3-5 working days

Manual

Inquire
Product Overview:
Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
Usage:
Reconstitute in PBS or others.
Stability:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage:
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
Stroage Buffer:
Lyophilized from 50mM Tris-cl,0.5mM EDTA ,300mM NaCl,pH 9.0
Precautions:
This product is for research use only, not for diagnostic or therapeutic use.