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Recombinant Human Dickkopf 1 (DKK1) Protein


Species Reactivity

Human

Source

Prokaryotic expression

Host

E. coli

Synonyms

DKK1; DKK-1; SK

Concentration

1 mg/mL

Form

Lyophilized or Liquid

Purity

> 90% as determined by SDS-PAGE

Residues

O94907

Tag

N-terminal His-tag

Purification

Affinity purification

Molecular Weight(MW)

12 kDa

Applications

Western blotting,ELISA;SDS-PAGE;Antigen;

Cat

AP50144HU

Size

100μg 500μg 1mg

Price

Inquire

Availability

3-5 working days

Manual

Inquire
Product Overview:
Dickkopf-related protein 1 is a protein that in humans is encoded by the DKK1 gene. This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow, plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Usage:
Reconstitute in PBS or others.
Stability:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage:
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
Stroage Buffer:
Lyophilized from 50mM Tris-cl,0.5mM EDTA ,300mM NaCl,pH 9.0
Precautions:
This product is for research use only, not for diagnostic or therapeutic use.