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Recombinant Human Protein disulfide isomerase (PDI) Protein


Species Reactivity

Human

Source

Prokaryotic expression

Host

E. coli

Synonyms

ERBA2L; PDI; PDIA1; PO4DB

Concentration

1 mg/mL

Form

Lyophilized or Liquid

Purity

> 95% as determined by SDS-PAGE

Residues

Gln 93-Gln 197 (P07237)

Tag

N-terminal His-tag

Purification

Affinity purification

Molecular Weight(MW)

12 kDa

Applications

Western blotting,ELISA;SDS-PAGE;Antigen;

Cat

AP50095HU

Size

100μg 500μg 1mg

Price

Inquire

Availability

3-5 working days

Manual

Inquire
Product Overview:
This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP
Usage:
Reconstitute in PBS or others.
Stability:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage:
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
Stroage Buffer:
Lyophilized from 20mM PB, 300mMNaCl,pH7.7
Precautions:
This product is for research use only, not for diagnostic or therapeutic use.