Product Details
| Species Reactivity |
Human |
| Source |
Prokaryotic expression |
| Host |
E. coli |
| Synonyms |
DNMT1; ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT |
| Concentration |
1 mg/mL |
| Form |
Lyophilized or Liquid |
| Purity |
> 90% as determined by SDS-PAGE |
| Residues |
Arg4-Asn111 (P26358) |
| Tag |
N-terminal His-tag |
| Purification |
Affinity purification |
| Molecular Weight(MW) |
13 kDa |
| Applications |
Western blotting,ELISA;SDS-PAGE;Antigen; |
Product Overview
DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene.
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities.
Usage
Reconstitute in PBS or others.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
Stroage Buffer
Lyophilized from 20 mM PB, 300 mM NaCl，pH 7.4
Precautions
This product is for research use only, not for diagnostic or therapeutic use.
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