Elevated level of active glucocorticoid (GC) deteriorates skin barrier function. 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is an NADPH-dependent enzyme converting inactive GC to active GC. Elevated active GC due to increased 11β-HSD1 expression might contribute to barrier impairment in aged skin and diabetic skin.
Product: Mouse Corticosteroid 11-beta-dehydrogenase isozyme 1 (HSD11B1) ELISA Kit
Microglia are highly heterogeneous as resident immune cells in the central nervous system. Although the proinflammatory phenotype of microglia is driven by the metabolic transformation in the disease state, the mechanism of metabolic reprogramming in microglia and whether it affects surrounding astrocyte progenitors have not been well elucidated.
Product: Mouse Leucine-rich repeat-containing protein 15 (LRRC15) ELISA Kit
Pub Date：2023-12-14 IF: 11.800
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by rapid progression and high mortality.
Product: Monkey Superoxide dismutase 1, soluble (SOD1) ELISA Kit
Heart failure is a serious condition that results from the extensive loss of specialized cardiac muscle cells called cardiomyocytes (CMs), typically caused by myocardial infarction (MI).
Product: Mouse Alanine Aminotransferase (ALT) ELISA Kit Mouse Aspartate Aminotransferase (AST) ELISA Kit
Pub Date：2023-11-20 IF: 17.100
Despite significant progress in cancer research, the complexity and heterogeneity of the disease still pose major challenges to accurate diagnosis and effective treatment.
Product: Human Protein argonaute-2 (EIF2C2) ELISA Kit
Pub Date：2023-09-27 IF: 9.300
Chronic obstructive pulmonary disease, or COPD, is a disease that commonly breaks the lower respiratory system triggered by continuous exposure to toxic inhalants resulting in oxidative stress accumulation and cascade inflammation process.
Product: Mouse Carboxyhemoglobin (HbCO) ELISA Kit