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Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease partly caused by gain-of-function mutations in superoxide dismutase 1 (SOD1). Here we developed RAG-17, an siRNA-targeting SOD1, using an accessory oligonucleotide conjugate platform for enhanced central nervous system (CNS) delivery.
Product: Monkey Superoxide dismutase 1, soluble (SOD1) ELISA Kit
Pub Date:2026-07-15 IF: 52.500
Sepsis is a life-threatening syndrome of organ dysfunction driven by a dysregulated immune response. Effective therapeutic strategies to restore immune homeostasis remain limited. Hypoacylated lipooligosaccharides (ALOS) from Akkermansia muciniphila have emerged as potential immunomodulatory postbiotics, yet their therapeutic potential in sepsis and the underlying mechanisms remain unexplored.
Product: Pig Tumor necrosis factor α (TNF-α) ELISA Kit Pig Interleukin 6 (IL-6) ELISA Kit
Pub Date:2026-07-02 IF: 17.100
Diabetic foot ulcer (DFU) represents a significant challenge in clinical management due to its complexity and the impaired wound-healing process associated with diabetes.
Product: Mouse Interleukin 6 (IL-6) ELISA Kit Mouse Tumor necrosis factor α (TNF-α) ELISA Kit Mouse Interleukin 10 (IL-10) ELISA Kit
Pub Date:2026-06-26 IF: 3.500
Cannabis is widely used during pregnancy, increasing with cannabis legalization, and has been associated with altered neurodevelopment, yet the precise molecular mechanisms remain poorly understood.
Product: Human Dopamine D2 receptor (D2R) ELISA Kit
Pub Date:2026-06-01 IF: 5.500
Chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESAs, trade name F-53B), an emerging substitute for perfluorooctane sulfonates (PFOS) used as mist suppressor in electroplating in China, has raised increasing attention due to its environmental persistence, bioaccumulation, and potential health risks.
Product: Rabbit Anti-Human LHR Polyclonal Antibody
Pub Date:2026-05-28 IF: 3.100
Postmenopausal osteoporosis is characterized by progressive bone loss and an increased risk of fractures, while current pharmacological approaches mainly suppress bone resorption and present long-term limitations.
Product: Rat Osteocalcin/Bone gla protein (OT/BGP) ELISA Kit Rat Tartrate-resistant acid phosphatase 5b (TRACP-5b) ELISA Kit Rat Cross linked C-telopeptide of type I collagen (CTX-I) ELISA Kit Rat Procollagen I N-terminal peptide (PINP) ELISA Kit
Pub Date:2026-05-19 IF: 1.300