Roles of TREM2 in degeneration of human nucleus pulposus cells via NF‐κB p65

Nuclear factor (NF)-κB p65 plays a key role in the development of intervertebral disc degeneration (IDD). Herein, we found that messenger RNA levels of human triggering receptor expressed on myeloid cells‐2 (TREM2) and NF‐κB p65 were upregulated and strongly positive correlated (r2 = 0.299, P = 0.0126) in nucleus pulposus (NP) tissues of patients with IDD.

Product: Human Tumor Necrosis Factor α (TNF-α) ELISA Kit  Human Interleukin-1 beta (IL1B) ELISA Kit  Human Interleukin 6 (IL-6) ELISA Kit 

Pub Date：2018-08-04   IF: 2.959

Antagonistic effects of different selenium sources on growth inhibition, oxidative damage, and apoptosis induced by fluorine in broilers

Fluorosis can induce oxidative stress through leading to reactive oxygen species (ROS) generation. Selenium (Se) can eliminate ROS by direct and indirect manners. In this study, therefore, we investigated the possible protective effects of sodium selenite (SS) and selenomethionine (Se-Met) on fluorine (F)-induced oxidative stress in broilers.

Product: Chicken Selenoprotein P (SEPP1) ELISA Kit

Pub Date：2018-06-13   IF: 2.216

NLRC3: A Novel Noninvasive Biomarker for Pulmonary Hypertension Diagnosis

The nucleotide-oligomerization domain (NOD)-like receptor subfamily C3 (NLRC3) is a newly discovered and incompletely characterized member of the NLR family which negatively regulates inflammatory responses. Inflammation is considered a critical pathogenesis in pulmonary hypertension (PH).

Product: Human NOD-like receptor family CARD domain containing 3 (NLRC3) ELISA Kit

Pub Date：2017-11-09   IF: 5.058

Reproductive and endocrine-disrupting toxicity of Microcystis aeruginosa in female zebrafish

Microcystis aeruginosa, a primary species in cyanobacterial blooms, is ubiquitously distributed in water. Microcystins (MCs) purified from M. aeruginosa can exert reproductive toxicity in fish. However, the effects of M. aeruginosa at environmentally relevant levels on the reproductive and endocrine systems of zebrafish are still unknown.

Product: Fish Vitellogenin (VTG) ELISA Kit

Pub Date：2017-11-01   IF: 4.208