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Breaking news on penicillin allergy

At some point you may have had a reaction to penicillin and were told you were allergic. And theres a good chance it has stayed in your chart throughout your childhood and into adulthood. But 9 of 10 Americans who think they have a penicillin allergy have either outgrown it or never had it in the first place.


Allergy patients equally satisfied with telemedicine and in-person appointments

a new study being presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Houston showed most parents of pediatric patients were more or equally satisfied with the treatment their children received during telemedicine visits for allergies and asthma.


Specific stimulation of T lymphocytes with erythropoietin for adoptive immunotherapy

Expression of erythropoietin receptor or of a functionally more potent mutant (EpoRm) promote T-cell survival and proliferation. EpoRm expression endows CAR-T cells with superior anti-tumor activity, an approach that could be applied to other adoptive T-cell therapies.


Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients withmyeloproliferative neoplasms

While scientists from University of Pavia found that in CALR-mutated MPNs, defective interaction between mutant calreticulin and SOCE proteins promotes megakaryocyte proliferation. Their research has been published in Blood recently.


Scientists identify genetic variation linked to severity of ALS

A discovery made several years ago in a lab researching asthma at Wake Forest School of Medicine may now have implications for the treatment of amyotrophic lateral sclerosis (ALS), a disease with no known cure and only two FDA-approved drugs to treat its progression and severity.


Improving research with more effective antibodies

A new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly.


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