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Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent

Pembrolizumab monotherapy showed durable antitumour activity and manageable safety in patients with metastatic triple-negative breast cancer. We aimed to examine whether the addition of pembrolizumab would enhance the antitumour activity of chemotherapy in patients with metastatic triple-negative breast cancer.

Date:2020-12-28

Blood phosphorylated tau 181 as a biomarker for Alzheimer´s disease

CSF and PET biomarkers of amyloid β and tau accurately detect Alzheimers disease pathology, but the invasiveness, high cost, and poor availability of these detection methods restrict their widespread use as clinical diagnostic tools.

Date:2020-12-28

Diseased cell fragments burst from pockets in immune cells to activate response

Researchers at the Francis Crick Institute have uncovered an important process in how our immune system detects signs of disease and activates a protective response.

Date:2020-12-28

COVID immunity lasts at least eight months, new data reveals

Australian researchers have revealed-for the first time-that people who have been infected with the COVID-19 virus have immune memory to protect against reinfection for at least eight months. The research is the strongest evidence for the likelihood that vaccines against the virus, SARS-CoV-2, will work for long periods.

Date:2020-12-28

Hepatitis C Virus Faces New Weapon: Novel Genetic Screening Method Can Identify Drug-Resistant HCV Strains

ScienceDaily-In recent human trials for a promising new class of drug designed to target the hepatitis C virus (HCV) without shutting down the immune system, some of the HCV strains being treated exhibited signs of drug resistance.

Date:2020-12-28

Study sheds light on immune mechanism that triggers cytokine storm typical of COVID-19

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.

Date:2020-11-27

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