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IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models

Pancreatic ductal adenocarcinoma (PDAC) and cancer-associated cachexia (CAC) are multifactorial and characterized by dysregulated inflammatory networks.

Date:2020-09-29

Circulating Insulin-like Growth Factor-I Concentrations and Risk of 30 Cancers: Prospective Analyses in UK Biobank

Circulating insulin-like growth factor I (IGF-I) is positively associated with the risks of colorectal, breast, and prostate cancer, but evidence for other less common cancers is limited.

Date:2020-09-29

Which antibodies are most effective against coronavirus?

Researchers Indu Khatri, Frank Staal and Jacques van Dongen from Leiden University Medical Center (LUMC) have published a perspective article in Frontiers in Immunology about coronavirus and its characteristic spike protein. They predict which antibodies would provide the best protection against the virus and which vaccines might help.

Date:2020-09-28

Some severe COVID-19 cases linked to genetic mutations or antibodies that attack the body

People infected by the novel coronavirus can have symptoms that range from mild to deadly. Now, two new analyses suggest that some life-threatening cases can be traced to weak spots in patients immune systems.

Date:2020-09-28

Vitamin D Levels May Affect Macular Degeneration Risk

Women With High Vitamin D Levels May Have Decreased Risk of Age-Related Macular Degeneration, Study Finds April 11, 2011 -- Women younger than 75 who get sufficient vitamin D in their diets appear to have a reduced risk of a leading cause of blindness, new research indicates.

Date:2020-09-28

Scientists describe how protein acts as courier in cell signaling pathways

Normal development, from fertilized egg to adult organism, depends on each cell receiving proper instructions from its environment. In response to such incoming information, receptors on a cells surface send signals to the nucleus that tweak gene expression and control cellular function.

Date:2020-09-28

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