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T cell immunity in the elderly

A study by Monash Biomedicine Discovery Institute (BDI) expands the understanding of the molecular pathways that control T cell function and survival and how it relates to declining T cell immunity in the elderly.


Study identifies potential approach to treat severe respiratory distress in patients with COVID-19

Early data from a clinical study suggest that blocking the Bruton tyrosine kinase (BTK) protein provided clinical benefit to a small group of patients with severe COVID-19.


Increasing Inhaled Steroids Curbs Asthma in Adults

For adults and adolescents with asthma being treated with inhaled glucocorticoids, with or without add-on therapy, the temporary quadrupling of the dose at the first sign of asthma control deterioration reduces the incidence of severe exacerbations by 19%, according to results from a new study.


Beer compound decreases weight gain and lowers cholesterol

Metabolic syndrome is a health condition affecting about 34% of adults in the US, putting them at risk for cardiovascular disease, diabetes, stroke and other diseases. Now, researchers from Oregon State University say a flavonoid found in hops and beer could reduce weight gain and improve markers of metabolic syndrome.


C9orf72 suppresses systemic and neural inflammation induced by gut bacteria

Recently, Aaron Burberry from Harvard University and his team published their research about 9orf72 suppresses systemic and neural inflammation induced by gut bacteria on Nature.


HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1α-dependent acyloxyacyl hydrolase expression

Liver dysfunction is strongly associated with poor survival of sepsis patients. Cytosolic lipopolysaccharide (LPS) sensing by Caspase-4/5/11 for pyroptosis activation is a major driver of the development of sepsis.


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