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Poly (I:C) causes failure of immunoprophylaxis to red blood cells expressing the KEL glycoprotein in mice

Polyclonal anti-D (RhIg) therapy has mitigated hemolytic disease of the newborn over the past half century, though breakthrough anti-D alloimmunization still occurs in some treated females.

Date:2020-04-30

Guselkumab in biologic-naive patients with active psoriatic arthritis (DISCOVER-2): a double-blind, randomised, placebo-controlled phase 3 trial

Guselkumab, a human monoclonal antibody that specifically inhibits IL-23 by binding the cytokines p19 subunit, was efficacious and demonstrated an acceptable benefit–risk profile in patients with active psoriatic arthritis who were naive to treatment with biologics.

Date:2020-04-30

Could vitamin D deficiency increase the risk of schizophrenia

Past research has linked vitamin D deficiency to increased bone aging, higher risk of chronic pain among men and even increased likelihood of death from all causes. Now, a new study suggests that individuals with vitamin D deficiency are at higher risk of schizophrenia.

Date:2020-04-18

Human skin suppresses inflammation after exposure to ultraviolet radiation

A study led by an NIHR Manchester Biomedical Research Centre scientist has identified, for the first time, how the human skin suppresses inflammation after exposure to ultraviolet radiation (UVR).

Date:2020-04-11

3 simple steps to support your immune health

Whether its wiping down our cart at the grocery store, washing ones hands properly for at least 20 seconds, or staying home when at all possible, we are all adjusting to a new normal to limit our exposure to COVID-19.

Date:2020-04-10

Sleep Irregularity and Risk of Cardiovascular Events

In March 2020, a study about Sleep Irregularity and Risk of Cardiovascular Events was issued on JACC. The cardiovascular system exhibits strong circadian rhythms to maintain normal functioning. Irregular sleep schedules, characterized by high day-to-day variability in sleep duration or timing, represent possibly milder but much more common and chronic disruption of circadian rhythms in the general population than shift work.

Date:2020-03-29

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