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Studies uncover details of ´exhausted′ immune cells in patients with chronic infections

Chronic viral infections and cancer can cause "killer" T cells in the immune system to take on a state of dysfunction or exhaustion.

Date:2021-07-30

You should know about autoimmune liver disease

Autoimmune liver disease is a common clinical disease type, which mainly refers to liver inflammatory lesions mediated by autoimmunity, including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC).

Date:2021-07-28

Scientists seek COVID protection boost for people with weakened immunity

How effective are COVID vaccines if your immune system is compromised by HIV, cancer or a recent organ transplant?Faced with very little data and fears that some of these patients could be particularly vulnerable to the virus scientists are seeking to figure out how to best protect them.

Date:2021-07-09

AID/APOBECs among important factors in body´s defence against SARS-CoV-2

AID and APOBEC proteins are important factors in the bodys immune response and offer fast and effective protection against a large number of DNA and RNA viruses.

Date:2021-07-09

WSX1 act as a tumor suppressor in hepatocellular carcinoma by downregulating neoplastic PD-L1 expression

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and ranks as the fifth leading cause of cancer-related mortality.

Date:2021-07-06

Developmental Consequences of Defective ATG7-Mediated Autophagy in Humans

Autophagy is the major intracellular degradation route in mammalian cells. Systemic ablation of core autophagy-related (ATG) genes in mice leads to embryonic or perinatal lethality, and conditional models show neurodegeneration.

Date:2021-07-06

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