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Objective To investigate the effects of sepsis and HIF-1α agonist or inhibitor on intestinal mucosal barrier function.Methods SD rats were randomly divided into sham operation group (sham), Sepsis group treating with cecal ligation and perforation (CLP), Sepsis+HIF-1α agonist group (sepsis + DMOG) receiving intraperitoneal injection of HIF-1α agonist DMOG (40 mg/kg) for 7 consecutive days before CLP, Sepsis+HIF-1α inhibitor group (sepsis+BAY87-2243) orally administered with HIF-1α inhibitor BAY87-2243 (9 mg/kg) for 3 consecutive days before CLP.
Product: Rat D-lactic acid ELISA Kit
Pub Date:2021-10-27 IF: 0.552
To investigate the feasibility and the value of using mitochondrial quality control (MQC)-related proteins as biomarkers in septic patients.The enrolled subjects were divided into four groups: healthy control group (n = 30), intensive care unit (ICU) control group (n = 62), septic nonshock group (n = 40), and septic shock group (n = 94). Serum levels of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), fission protein 1 (Fis1), mitofusin2 (Mfn2), and Parkin were measured by enzyme-linked immunosorbent assay at the time of enrollment for all groups. Clinical parameters and laboratory test results were also collected.
Product: Human Mitochondrial fission 1 protein (FIS1) ELISA Kit Human Mitofusin-2 (MFN2) ELISA Kit
Pub Date:2021-09-01 IF: 3.454
The experiment studied the effect of adding yeast culture to feed on growth performance, nutrient digestibility, fermentation parameters and antioxidant function of Simmental hybrid cattle.
Product: Bovine Glutathione peroxidase (GSH-PX) ELISA Kit Bovine Catalase (CAT) ELISA Kit Bovine Malondialdehyde (MDA) ELISA Kit Bovine Super Oxide Dismutase (SOD) ELISA Kit
Pub Date:2021-08-26 IF: 1.39
Nano-silver antibacterial dressings and hydrogels are both new types of dressings used for the treatment of infected wounds. Recombinant human basic fibroblast growth factor is an active peptide drug commonly used for open wounds.
Product: Human Superoxide Dismutase (SOD) ELISA Kit
Pub Date:2021-06-02 IF: 1.650
DOK is a new type of regulatory protein family that participates in the regulation of tumor cell growth. However, most of the studies are conducted in cell lines, and systematic studies have not been conducted in human tumors.
Product: Rabbit Anti-Human Dok-1 Polyclonal Antibody Rabbit Anti-Human Dok-2 Polyclonal Antibody Rabbit Anti-Human Dok-4 Polyclonal Antibody Rabbit Anti-Human Dok-6 Polyclonal Antibody
Pub Date:2021-06-12 IF: 6.992
Recent studies suggest potential benefits of applying L-carnitine in the treatment of cancer cachexia, but the precise mechanisms remain unknown. This study was conducted to determine the mechanism by which L-carnitine reduces cancer cachexia.
Product: Mouse Interleukin-1 beta (IL1B) ELISA Kit Mouse Interleukin 6 (IL-6) ELISA Kit Mouse Tumor necrosis factor α (TNF-α) ELISA Kit
Pub Date:2021-06-02 IF: 3.211