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The protective effects of HIF-1α activation on sepsis induced intestinal mucosal barrier injury in rats model of sepsis

The integrity of the intestinal barrier is critical for protecting the host against the pathogen. The role of hypoxia-inducible factor-1α (HIF-1α) in the intestinal barrier disfunction related to sepsis remained unclear.

Product: Rat D-lactic acid ELISA Kit

Pub Date:2022-05-16   IF: 3.240

Higher Serum RCAN2 Levels Are Associated with Metabolically Unhealthy Individuals, Either with Obesity or Not

Regulator of calcineurin 2 (RCAN2) has been documented to cause weight gain and related pathology and metabolism abnormalities in animal researches. The aim of the study was to compare serum RCAN2 concentrations in metabolically healthy (MH) and metabolically unhealthy (MUH) individuals.

Product: Human Calcipressin-2 (RCAN2) ELISA Kit

Pub Date:2022-04-21

Elevated Serum Regulator of Calcineurin 2 is Associated With an Increased Risk of Non-Alcoholic Fatty Liver Disease

The promoting effect of the regulator of calcineurin 2 (RCAN2) in hepatic steatosis has been observed in animal studies. However, the association of RCAN2 with non-alcoholic fatty liver disease (NAFLD) in humans remains unclear.

Product: Human Calcipressin-2 (RCAN2) ELISA Kit  Mouse Calcipressin-2 (RCAN2) ELISA Kit 

Pub Date:2022-03-16   IF: 5.810

Effect of dexmedetomidine up-regulating HIF-1ɑ on intestinal mucosal barrier injury related to sepsis in rats

Dexmedetomidine (DEX), a highly selective α2 receptor agonist. DEX can inhibit the release of inflammatory factors in septic rats.

Product: Rat D-lactic acid ELISA Kit

Pub Date:2022-03-29

Association between IL-10 systemic low level and highest pain score in patients during symptomatic SARS-CoV-2 infection

Despite the wide variety of Covid-19 symptoms, pain and the related mechanisms underlying unsettled nociceptive status are still under-prioritized. Understanding the complex network of Covid-19-related pain may result in new lines of study.

Product: Human Substance P (SP) ELISA Kit

Pub Date:2022-01-26   IF: 3.183

Myosin light chain 9 promotes the proliferation, invasion, migration and angiogenesis of colorectal cancer cells by binding to Yes-associated protein 1 and regulating Hippo signaling

Colorectal cancer is a common type of cancer with high incidence and poor prognosis. Increased expression of myosin light chain 9 (MYL9) has been reported in early-stage and recurrent colorectal cancer tissues.

Product: Human Vascular Endothelial cell Growth Factor (VEGF) ELISA Kit

Pub Date:2022-01-03   IF: 3.269

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