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Recombinant Human X-box-binding protein 1 (XBP1) Protein

  • Cat.No.: AP50175HU

  • Reactivity: Human

To Purchase AP50175HU

Size:
100μg 500μg
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Product Details

Species Reactivity Human
Source Prokaryotic expression
Host E. coli
Synonyms XBP1; TREB5; XBP-1; XBP2
Concentration 1 mg/mL
Form Lyophilized or Liquid
Purity > 95% as determined by SDS-PAGE
Residues Thr123-Pro225 (P17861)
Tag N-terminal His-tag
Purification Affinity purification
Molecular Weight(MW) 12 kDa
Applications Western blotting,ELISA;SDS-PAGE;Antigen;

Product Overview

X-box binding protein 1, also known as XBP1, is a protein which in humans is encoded by the XBP1 gene. The XBP1 gene is located on chromosome 22 while a closely related pseudogene has been identified and localized to chromosome 5.[3] The XBP1 protein is a transcription factor that regulates the expression of genes important to the proper functioning of the immune system and in the cellular stress response. The X-box binding protein 1 (XBP-1) is a transcription factor containing a bZIP domain. It was first identified by its ability to bind to the X-box, a conserved transcriptional element in the promoter of the human leukocyte antigen (HLA) DR alpha.
 

Usage

Reconstitute in PBS or others.
 

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 

Storage

Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
 

Stroage Buffer

Lyophilized from 50mM Tris-HCL,0.5mM EDTA,300mM NaCl,pH 9.0
 

Precautions

This product is for research use only, not for diagnostic or therapeutic use.