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Recombinant Human Major Histocompatibility Complex Class I Related Gene Protein (MR1) Protein

  • Cat.No.: AP50148HU

  • Reactivity: Human

To Purchase AP50148HU

Size:
100μg 500μg
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Product Details

Species Reactivity Human
Source Prokaryotic expression
Host E. coli
Synonyms MR1; HLALS; MR-1
Concentration 1 mg/mL
Form Lyophilized or Liquid
Purity > 90% as determined by SDS-PAGE
Residues Q95460
Tag N-terminal His-tag
Purification Affinity purification
Molecular Weight(MW) 12 kDa
Applications Western blotting,ELISA;SDS-PAGE;Antigen;

Product Overview

Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
 

Usage

Reconstitute in PBS or others.
 

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 

Storage

Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
 

Stroage Buffer

Lyophilized from 50mM Tris-cl,0.5mM EDTA ,300mM NaCl,pH 9.0
 

Precautions

This product is for research use only, not for diagnostic or therapeutic use.