Product Details
| Species Reactivity |
Human |
| Source |
Prokaryotic expression |
| Host |
E. coli |
| Synonyms |
PRDX4; AOE37-2; HEL-S-97n; PRX-4 |
| Concentration |
1 mg/mL |
| Form |
Lyophilized or Liquid |
| Purity |
> 95% as determined by SDS-PAGE |
| Residues |
Cys51-Asp151 (Q13162) |
| Tag |
N-terminal His-tag |
| Purification |
Affinity purification |
| Molecular Weight(MW) |
12 kDa |
| Applications |
Western blotting,ELISA;SDS-PAGE;Antigen; |
Product Overview
Peroxiredoxin-4 is a protein that in humans is encoded by the PRDX4 gene.
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
Usage
Reconstitute in PBS or others.
Stability
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage
Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
Stroage Buffer
Lyophilized from 50mM Tris-HCL，0.5mM EDTA，300mM NaCl，pH 9.0
Precautions
This product is for research use only, not for diagnostic or therapeutic use.
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