Women of childbearing age cancer patients during radiotherapy and targeting effect oocyte DNA damage response during chemotherapy, often choose to protect their fertility. Recently, a study was published in the journal, Trends in Cancer, researchers from the university of Texas m.d. Anderson Cancer center, they found that through the research developed a new method, the method in the treatment of Cancer in the process of the female individual can block apoptosis effect to protect womens bodys fertility.
Researcher, Bolcun - Filas said, now for us, the biggest good news is more and more aged women can keep away from cancer deaths, it indirectly reflects the emergence of more effective cancer therapy in todays society. But many cancer treatments will increase a womans risk of ovarian dysfunction and infertility. At the same time, assisted reproductive technology can help treat infertility but it usually doesnt protect women ovarian function of the natural body, the natural function of ovary is very important for womens reproductive health.
Many cancer therapies can trigger cell DNA damage, will not only affect cancer cell, but also affect the bodys normal tissues, such as ovarian, an aspect of the natural response to injury is thought to through the way of cell apoptosis, or programmed cell death to effectively remove damage oocytes. Recent results indicate that in mice, targeted action to participate in the special proteins or cell apoptosis can protect the body oocytes. And inhibition of exposure to radiation condition of female infertility.
In this study, the researchers reviewed a large number of related research, how they revealed the cancer treatment induced oocyte apoptosis sexual death occurs. The related research also can help scientists design better protective therapy. Finally, the researchers said, and a better understanding of oocytes response to radiation and anti-cancer drugs may help us to solve new targets, in order to later development of specific therapy to inhibit cancer women ovarian function failure body
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